1st Edition
by Frederick A. Villamena (Author)
Sets the stage for the development of better diagnostic techniques and therapeutics
Featuring contributions from an international team of leading clinicians and biomedical researchers, Molecular Basis of Oxidative Stress
reviews the molecular and chemical bases of oxidative stress,
describing how oxidative stress can lead to the development of cancer
and cardiovascular and neurodegenerative diseases. Moreover, it explains
the potential role of free radicals in both the diagnosis and the
development of therapeutics to treat disease.
Molecular Basis of Oxidative Stress
is logically organized, beginning with a comprehensive discussion of
the fundamental chemistry of reactive species. Next, the book:
- Presents new mechanistic insights into how oxidative damage of biomolecules occurs
- Examines how these oxidative events effect cellular metabolism
- Investigates
the role of oxidative stress in the pathogenesis of cancer,
neurodegenerative disease, cardiovascular disease, and cystic fibrosis
- Explores opportunities to improve the diagnosis of disease and the design of new therapeutic agents
Readers
will find much novel information, including new radical chemistries and
the latest discoveries of how free radicals react with biomolecules.
The contributors also present recent findings that help us better
understand the initiation of oxidative stress and the mechanisms leading
to the pathogenesis of various diseases.
Throughout the book,
the use of molecular structures helps readers better understand redox
chemistry. In addition, plenty of detailed figures illustrate the
mechanisms of oxidative stress and disease pathogenesis.
Examining everything from the basic chemistry of oxidative stress to the pathogenesis of disease, Molecular Basis of Oxidative Stress
will help readers continue to explore the nature of oxidative stress
and then use that knowledge to develop new approaches to prevent,
detect, and treat a broad range of disease conditions.
