1st Edition
by N. Balakrishnan (Editor)
A complete guide to the key statistical concepts essential for the design and construction of clinical trials
As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents
a timely and authoritative reviewof the central statistical concepts
used to build clinical trials that obtain the best results. The
referenceunveils modern approaches vital to understanding, creating, and
evaluating data obtained throughoutthe various stages of clinical trial
design and analysis.
Accessible and comprehensive, the first
volume in a two-part set includes newly-written articles as well as
established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating
a variety of statistical concepts and principles such as longitudinal
data, missing data, covariates, biased-coin randomization, repeated
measurements, and simple randomization, the book also provides in-depth
coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features:
- Detailed
chapters on the type of trial designs, such as adaptive, crossover,
group-randomized, multicenter, non-inferiority, non-randomized,
open-labeled, preference, prevention, and superiority trials
- Over 100 contributions from leading academics, researchers, and practitioners
- An
exploration of ongoing, cutting-edge clinical trials on early cancer
and heart disease, mother-to-child human immunodeficiency virus
transmission trials, and the AIDS Clinical Trials Group
Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is
an excellent reference for researchers, practitioners, and students in
the fields of clinicaltrials, pharmaceutics, biostatistics, medical
research design, biology, biomedicine, epidemiology,and public health.
