1st Edition
by Chris D. Geddes (Editor)
Discover how metal-enhanced fluorescence is changing traditional concepts of fluorescence
This
book collects and analyzes all the current trends, opinions, and
emerging hot topics in the field of metal-enhanced fluorescence (MEF).
Readers learn how this emerging technology enhances the utility of
current fluorescence-based approaches. For example, MEF can be used to
better detect and track specific molecules that may be present in very
low quantities in either clinical samples or biological systems. Author
Chris Geddes, a noted pioneer in the field, not only explains the
fundamentals of metal-enhanced fluorescence, but also the significance
of all the most recent findings and models in the field.
Metal-enhanced
fluorescence refers to the use of metal colloids and nanoscale metallic
particles in fluorescence systems. It offers researchers the
opportunity to modify the basic properties of fluorophores in both near-
and far-field fluorescence formats. Benefits of metal-enhanced
fluorescence compared to traditional fluorescence include:
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Increased efficiency of fluorescence emission
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Increased detection sensitivity
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Protect against fluorophore photobleaching
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Applicability to almost any molecule, including both intrinsic and extrinsic chromophores
Following
a discussion of the principles and fundamentals, the author examines
the process and applications of metal-enhanced fluorescence. Throughout
the book, references lead to the primary literature, facilitating
in-depth investigations into particular topics.
Guiding readers
from the basics to state-of-the-technology applications, this book is
recommended for all chemists, physicists, and biomedical engineers
working in the field of fluorescence.